GREEN SYNTHESIS USING HERBAL FORMULATION (AZADIACHTA INDICA & ZINGEBERG OFFICINACLE) MEDIATED IRON NANOPARTICLES & ITS FREE RADICLE SCAVENGING ACTVITY.
Main Article Content
Abstract
Introduction:
Azadirachta indica, commonly known as margosa, neem is a tree in the mahogany family Meliaceae. Zingiber officinale known as ginger is a flowering plant whose rhizome, ginger root or ginger, is widely used as a spice and a folk medicine. Herbal formulation-mediated iron nanoparticles, utilizing Azadirachta indica (Neem) and Zingiber officinale (Ginger), show promise in scavenging free radicals. These nanoparticles offer potential applications in antioxidative therapy, drug delivery systems, and environmental remediation(1)
Aim:
The aim of the research is to investigate the potential of herbal formulation-mediated iron nanoparticles, using Azadirachta indica (Neem) and Zingiber officinale (Ginger), in scavenging free radicals and their applications in antioxidative therapy, drug delivery systems, and environmental remediation.
Materials and Methods
- Weighing of sample of Azadirachta indica (Neem) and Zingiber officinale (Ginger)
- Preparation of extract Azadirachta indica (Neem) and Zingiber officinale (Ginger)
- Filtering the extract
- Centrifugation of the extract
- Sample with nanoparticles
- Iron nanoparticles with the Azadirachta indica (Neem) and Zingiber officinale (Ginger) extract
Results
the results shows a close difference between the standard and the tests done as we increase the concentration the strength of the herbal formulation
Discussion
from the above results from the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay,H2O2 assay and the Ferric reducing antioxidant power (FRAP) assay we can see that A. indica & Z. officinale (Fe203NPs) is close to the standard.This proves the efficiency of A. indica & Z. officinale (Fe203NPs)
Conclusion
From the above result and discussion we can say that the combination of A. indica & Z. officinale (Fe203NPs) can be used as a alternative herbal remedy as it is nearly close to the standard drug’s efficiency
Scope for future research
For a future research maybe a larger sample size and ways to concentrate more of A. indica & Z. officinale or a different combination can be used