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Dr. Deepali Janugade, Dr. Rajsinh V. Mohite, Dr. Satish V. Kakade


Introduction: Liver cirrhosis is a progressive and irreversible condition characterized by the replacement of healthy liver tissue with fibrous scar tissue, ultimately leading to liver dysfunction. It is a significant global health concern, affecting millions of individuals worldwide and resulting in substantial morbidity and mortality. Common causes of liver cirrhosis include chronic alcohol consumption, viral hepatitis, non-alcoholic fatty liver disease (NAFLD), and autoimmune liver diseases.
Background: Liver cirrhosis represents a significant global health burden, with limited treatment options beyond symptom management and liver transplantation. Emerging therapies, including antifibrotic agents, immunomodulators, regenerative medicine, and precision medicine, hold promise for improving outcomes for patients with liver cirrhosis.
Results & Observations: Current therapies for liver cirrhosis primarily focus on managing symptoms and complications, while liver transplantation remains the definitive treatment for end-stage disease. Emerging therapies, such as antifibrotic agents and immunomodulators, have shown promising results in preclinical and early-phase clinical trials. These therapies aim to target the underlying mechanisms of cirrhosis, including fibrosis, inflammation, and immune dysregulation.
Conclusion: Emerging therapies offer new hope for patients with liver cirrhosis by addressing the underlying mechanisms of the disease and potentially slowing down or reversing its progression. Further research and clinical trials are needed to evaluate the safety and efficacy of these treatments and optimize their use in clinical practice. Early detection and intervention remain crucial in improving outcomes for patients with liver cirrhosis, highlighting the importance of continued research and innovation in this field.

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How to Cite
Dr. Satish V. Kakade, D. D. J. D. R. V. M. (2024). LIVER CIRRHOSIS: AN OVERVIEW OF CURRENT AND EMERGING THERAPIES. Obstetrics and Gynaecology Forum, 34(3s), 514–521. Retrieved from

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