ASSOCIATION OF PLACENTAL ALPHA 1 MICROGLOBULIN, FETAL FIBRONECTIN AND TSH IN 2ND AND 3RD TRIMESTER PREGNANT WOMEN
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Abstract
Abstract
Introduction: The second and third trimesters of pregnancy are critical periods for maternal and fetal health. Placental Alpha 1 Microglobulin (PAMG-1), Fetal Fibronectin (fFN), and Thyroid-Stimulating Hormone (TSH) are important biomarkers that may play a role in predicting complications such as preterm labor, thyroid dysfunction, and placental insufficiency. This study aims to explore the association between these biomarkers and pregnancy outcomes in the second and third trimesters.
Aims: The aim of our study is to assees the association of placental alpha microglobulin-1,fibronectin and TSH in 2nd and 3rd trimester
Materials and Methods: It was a prospective observational study, was conducted one year obstetric and gynecology department in IGIMS, PATNA.51 Patients were included in this study
Results: In Multigravida, 9(40.9%) patients had Backache, 10 (45.5%) patients had Pain Abdomen and 3 (13.6%) patients had Pain Abdomen + Backache. In Primigravida, 10 (34.5%) patients had Backache, 15(51.7%) patients had Pain Abdomen and 4(13.8%) patients had Pain Abdomen + Backache. Association of Chief Complain with Group was not statistically significant (p=0.8873).In Multigravida, 4(18.2%) patients had Modrate Anemia .In Primigravida, 5(17.2%) patients had Modrate Anemia. Association of Medical History with Group was not statistically significant (p=0.7995).
Conclusion: We conclude that demonstrates a significant association between Placental Alpha 1 Microglobulin (PAMG-1), Fetal Fibronectin (fFN), and Thyroid-Stimulating Hormone (TSH) levels in pregnant women during the second and third trimesters, and their relationship with adverse pregnancy outcomes.