INVESTIGATING PLACENTAL BIOMARKERS AS PREDICTORS OF BIRTH WEIGHT AND NEONATAL HEALTH

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Dr. Anjali S. Patil, Dr. U. T. Mane, Dr. Rajsinh V. Mohite

Abstract

Introduction: The placenta plays a crucial role in facilitating nutrient exchange, endocrine regulation, and immunomodulation during pregnancy. Placental biomarkers, including insulin-like growth factors, leptin, cortisol, and microRNAs, have been implicated in fetal growth regulation and neonatal health.
Objective: This study aims to explore the association between placental biomarkers and birth weight, as well as their impact on neonatal health. By reviewing existing literature and analyzing relevant research findings, we seek to elucidate the potential clinical implications of placental biomarker analysis in prenatal care.
Results: Our analysis reveals significant correlations between placental biomarkers and birth weight, with alterations in biomarker levels associated with adverse neonatal outcomes such as respiratory distress syndrome, hypoglycemia, and neurodevelopmental disorders. Methodological approaches for assessing placental biomarkers vary, ranging from immunohistochemistry to next-generation sequencing, each offering unique advantages and limitations.
Conclusion: Placental biomarkers hold promise as predictors of birth weight and indicators of neonatal health status. Integrating biomarker screening into routine prenatal care protocols may enable early identification of high-risk pregnancies and facilitate personalized interventions to optimize maternal-fetal health.

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How to Cite
Dr. Rajsinh V. Mohite, D. A. S. P. D. U. T. M. (2024). INVESTIGATING PLACENTAL BIOMARKERS AS PREDICTORS OF BIRTH WEIGHT AND NEONATAL HEALTH. Obstetrics and Gynaecology Forum, 34(3s), 594–601. Retrieved from https://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/321
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