ADVANCEMENTS IN FERTILITY PRESERVATION TECHNIQUES FOR WOMEN UNDERGOING CANCER TREATMENT: A PROSPECTIVE STUDY

Abstract

Abstract

Fertility preservation (FP) is a vital consideration in cancer care for young women undergoing gonadotoxic treatments. This prospective, multi-center study aims to assess the effectiveness, safety, and patient satisfaction of various FP methods among women diagnosed with cancer. Over two years, 200 participants were offered embryo cryopreservation, oocyte cryopreservation, ovarian tissue cryopreservation, and pharmacological ovarian protection, with experimental techniques such as in vitro maturation (IVM) and artificial ovary technologies available for a subset of patients. Primary outcomes included preservation of ovarian function, pregnancy rates, and patient satisfaction. Results indicate embryo and oocyte cryopreservation as the most effective FP methods in terms of pregnancy and satisfaction, while ovarian tissue cryopreservation provided viable options, particularly for young patients. Findings underscore the importance of personalized FP counseling to support reproductive outcomes for female cancer patients.