VAGINAL VERSUS RECTAL MISOPROSTOL BEFORE LAPAROTOMIC MYOMECTOMY
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Abstract
Background: Leiomyoma is benign, monoclonal tumor of the smooth muscle cells of the myometrium. It is much denser than normal myometrium. It affects mostly women during reproductive age; rarely found before menarche & usually regress after menopause.
Aim: to compare among vaginal & rectal misoprostol-as a preoperative medication-in controlling blood loss throughout myomectomy
Patients and methods: From January 2022 to January 2023, the Zagazig University Hospitals' department of obstetrics and gynecology hosted this randomized controlled experiment.
Results: There was no statistically significant difference in pre-operative mean hemoglobin, 24 hours postoperative hemoglobin content, pulse, need for blood transfusion, diastolic and systolic blood pressure among both groups (p-value>0.05). Regarding peri-operative complications & length of hospital stay in both groups, febrile morbidity and need for additional analgesics were statistically significantly higher in G2 than G1 (4.5% versus 31.8% and 9.1% versus 40.9% respectively) (p-value=0.04* & 0.01* respectively .However, no statistically significant difference among both groups with regard to hospital stay, need for hysterectomy& other complications as diarrhorea and abdominal cramps (p-value >0.05).