DETECTION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA FROM IRAQI WOMEN INFECTED WITH POLYCYSTIC OVARY SYNDROME
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Abstract
Abstract
Polycystic ovary syndrome is an endocrine disorder affecting women of reproductive age with a worldwide prevalence of approximately 8-13%. In patients with PCOS, numerous small cysts (fluid-filled sacs) form in the ovaries. Typical clinical features include abnormally high levels of androgens, irregular menstrual cycles, hirsutism, acne, obesity, and infertility. PCOS pathogenesis remains elusive, but emerging research highlights the role of human microbiome in its occurrence and progression . the total number of samples 60 vaginal swabs. Vaginal swab samples were collected from women with polycystic ovary syndrome. During the period between 10 November 2023 and 20 February 2024 in Mosul City hospitals (Al-Khansa Teaching Hospital and Al-Salam Teaching Hospital), included different age groups ranging from 18 to 45 years. The aim of this study was to detect gram positive and gram negative bacteria in high vaginal swab from polycystic ovary syndrome. The result showed 15 were Gram-positive bacterial isolates (25%) and 45 were Gram-negative bacterial isolates (75%) . The result showed that the vaginal infection more frequent in age between (27-35) years old. According to age groupings, the age group(27-35)years old had the highest prevalence of vaginal infection with bacteria among patients (26; 43.34 %), 4 patients (6.67%), for Gram-positive bacterial. Conclusion there is microbial diversity in the vaginal microbiota. Incidence with Gram-negative bacteria were predominant more than Gram-positive bacteria in PCOS patients especially Staphylococcus. spp and E. coli in PCOS women.