CLINICAL AND NEUROIMAGING EVALUATION IN SEVERE PREECLAMPSIA AND ECLAMPSIA WITH OBSTETRIC OUTCOME

Abstract

Abstract

Introduction: Preeclampsia and eclampsia are two clinical situations that are exclusively associated with pregnancy. Preeclampsia is defined as the new onset of hypertension (blood pressure [BP] ≥140/90) and either proteinuria or end-organ dysfunction or both after 20 weeks of gestational in women who was previously normotensive.

Aims: The aim to study the neurological complication in severe preeclampsia and eclampsia.

Materials and method: The present study was a Prospective longitudinal type of observational study. This Study was conducted from February 2018 to May 2019 at department of Obstetrics & Gynaecology, Calcutta National Medical College, Kolkata. Total 50 patients were included in this study.

Result: In our study most of the patients were presented with Eclampsia (62 %) and 38 % presented with severe eclampsia. In above table 70 % had GCS more than 13 and 30 % had GCS less than 13. 81 % patients had normal opthalmoscopic findings and 4 patients (19%) had abnormal opthalmoscopic findings like constriction of retinal artery, cotton wool spots. In this above table 56 % patients had proteinuria + 2 by urine dipstick, 22 % had +3 proteinuria, 20 % had +1 & 2 % had +4 proteinuria. Occipital lobe of brain was most common area of brain involved (78.57%) followed by Parietal Lobe (75 %).

Conclusion: In conclusion, comprehensive clinical and neuroimaging evaluations play a pivotal role in the management of severe preeclampsia and eclampsia. These assessments not only aid in understanding the extent of cerebral involvement but also facilitate timely interventions that can mitigate maternal and fetal risks. By integrating clinical findings with advanced imaging techniques, healthcare providers can make more informed decisions, leading to improved obstetric outcomes. Early diagnosis, prompt treatment, and continuous monitoring are essential in reducing the morbidity and mortality associated with these hypertensive disorders of pregnancy.