A COMPARATIVE STUDY OF PRITCHARDS REGIMES WITH ZUSPAN’S REGIMEN IN THE MANAGEMENT OF ECLAMPSIA AND PRE-ECLAMPSIA

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Dr. Kottem Sahithi, Dr. Rachakonda Swetha, Dr. S. Mubina

Abstract

Abstract

Aim: In the present study, intravenous magnesium sulfate (Zuspan's regimen) compared with the standard Pritchards regimen.


Methodology: The present study is conducted in District Head quarter Hospital, Apollo Institute of Medical Sciences and Research, The Apollo Medical College, Chittoor from September 2021 to August 2023 for a period of 24 months.  It is a tertiary care center with a high number of referral cases of preeclampsia and eclampsia from surrounding rural areas.


Results: In the present study, the maximum number of cases is from a rural background, with low socioeconomic status and were unbooked cases. The majority are primigravidae with a mean age of 25.02 years   In the present study, 74% of cases from both groups are primigravida. In terms of efficacy in preventing recurrence of convulsions, 6% of cases in the Pritchards group, and 4% of cases in the Zuspans group had recurrences. Hence recurrence is more common with Pritchards regimen. 4% cases reported loss of knee jerks in pritchards regimen, 2% reported in zuspans regimen.  With standard pritchards regimen, toxicity is high compared to the zuspans regimen.  Zuspans regimen is as effective as Pritchard in preventing eclamptic convulsions in severe preeclampsia cases. It is our policy to give Magnesium sulfate prophylaxis to all patients of severe preeclampsia cases.   The common mode of delivery is by vaginal route .64 % and 62 % vaginal delivery rate is recorded in the Pritchards and Zuspans group, respectively. Maternal complications are comparable in both groups and may be due to  pathological implications of disease perse and not directly due to MgSO4.  No maternal deaths were reported in the study.


Conclusion: we may conclude that the awareness regarding antenatal checkups among the poor population is still deficient, resulting in poor maternal and fetal outcomes. Eclampsia could be predicted and effectively prevented if there is proper antenatal booking, and clinical obstetrics and biochemical assessment of pregnant women who are unaware of prenatal care and its importance. Early identification of risk factors for pre-eclampsia is also essential. 


 

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How to Cite
Dr. S. Mubina, D. K. S. D. R. S. (2024). A COMPARATIVE STUDY OF PRITCHARDS REGIMES WITH ZUSPAN’S REGIMEN IN THE MANAGEMENT OF ECLAMPSIA AND PRE-ECLAMPSIA. Obstetrics and Gynaecology Forum, 34(3s), 2503–2508. Retrieved from https://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/737
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