PREVALENCE AND SEVERITY OF OSTEOPOROSIS IN INDIA: VITAMIN K2 OFFERS FOR BREAKING THE OSTEOPOROSIS CYCLE
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Abstract
Objective: This study in Salem district, India, seeks to fill a knowledge gap by assessing osteoporosis prevalence, investigating the impact of vitamin K2-7 on bone health, and identifying socio- demographic factors associated with the condition.
Methods: A prospective cross-sectional study employed a 30-question questionnaire to gather data from 405 participants (74 males, 331 females) attending private and government hospitals. The survey covered demographics, medical history, dietary habits (including vitamin K2-7 intake), and social factors like literacy. Statistical analyses, including gender and vitamin K2-7 -based severity assessments, were performed. Statistical analysis is shown as number, percentages. To analyses the difference between the groups, chi- square tests is used to compare osteoporosis patients based on vitamin K2-7 supplement intake, with a general and specific analysis for comprehensive insights. P< 0.05 was considered to show significant associations. Graph Pad Prism version 10.1.2 facilitated robust data analysis
Results: An alarming 81.72% of participants, predominantly females, exhibited signs of osteoporosis. The higher prevalence in females was linked to factors like breastfeeding history, age at menopause, and oestrogen levels. Illiteracy rates of 60.9% highlighted significant awareness gaps about osteoporosis and bone health. Calcium intake trends varied, but interestingly, vitamin K2-7 intake demonstrated a potential correlation with reduced osteoporosis severity in both males and females. Concerns arose regarding the long- term impact of bisphosphonates, commonly prescribed medications for osteoporosis, on bone quality.
Conclusion: Vitamin K2-7’s potential association with reduced osteoporosis severity, coupled with its influence on cardiovascular health, underscores the need for a nuanced approach to medication choices and increased awareness amongst both healthcare providers and patients. Further research is essential to fully elucidate the benefits of vitamin K2-7 and its potential integration into management strategies for osteoporosis and cardiovascular health in India.