DETECTING THE EFFECT OF VITAMIN K2 DEFICIENCY IN PATIENTS WITH DIABETES MELLITUS AND CARDIOVASCULAR DISEASE

Abstract

Abstract

Object:  The current study aimed to find the correlation between vitamin K2 and chronic diseases such as diabetes and cardiovascular disease by studying a number of physiological and biochemical variables represented by RBS, HbA1c, lipid profile, liver enzymes, as well as antioxidants in men with diabetes and cardiovascular disease in Baghdad.

Subject:  The study included 80 people whose ages ranged between (15-75) years. Samples were collected from people visiting Al-Imam Al-Kazemin Medical City in Baghdad - Iraq. The experiment was designed into four groups. The first group included 20 healthy people representing the control group. The second group included 20 people with type 1 diabetes (completely dependent on insulin), the third group included 20 people with type 2 diabetes (non-insulin dependent), and the fourth group included 20 people suffering from cardiovascular disease (CVD).

Result:  The results indicated that there is a relationship between the concentration of vitamin K2 level and the variables that were found in the study, as there was a significant decrease in the concentration of vitamin K2 in all groups of patients compared to the control group, While the levels of only HDL in the lipid profile, as well as GSH, decreased for all groups of patients compared to the control group.

Conclusion: conclude from all the results that there is a significant effect of vitamin K2 in improving insulin sensitivity in people with diabetes, thus reducing the risk of diabetes and also important in the prevention and treatment of arterial calcifications and cardiovascular disease.