PHYSICOCHEMICAL INFLUENCE ON MEDICAL DEVICE SURFACES AND BIOFILM FORMATION: CONSIDERATIONS IN GENERAL SURGERY

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Dr Krutika Vichare, Dr V V Kanase, Dr Akshata Hanamshetti

Abstract

Abstract
Corynebacterium striatum, a Gram-positive bacillus, poses a significant concern in general surgery due to its potential to cause nosocomial outbreaks and various invasive infections, including sepsis and endocarditis. Despite its clinical relevance, there remains limited understanding of the virulence factors contributing to healthcare-associated infections by Corynebacterium spp., including C. striatum, particularly in the context of general surgical procedures. This study investigates the physicochemical influence on medical device surfaces and its correlation with biofilm formation, offering insights specifically tailored to the field of general surgery. Utilizing electron microscopy and quantitative analysis techniques, we examine the adherence of C. striatum to both hydrophilic (e.g., glass) and hydrophobic (e.g., polyurethane) surfaces commonly encountered in surgical settings. Our findings underscore the critical role of biofilm formation in C. striatum infections associated with general surgery. We observe varying adherence intensities and complex biofilm structures, highlighting the need for proactive measures to mitigate the risk of nosocomial outbreaks. This research emphasizes the importance of understanding the physicochemical properties of medical device surfaces in the context of general surgical procedures to inform strategies for infection control and patient safety.

 


 

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How to Cite
Dr Akshata Hanamshetti, D. K. V. D. V. V. K. (2024). PHYSICOCHEMICAL INFLUENCE ON MEDICAL DEVICE SURFACES AND BIOFILM FORMATION: CONSIDERATIONS IN GENERAL SURGERY . Obstetrics and Gynaecology Forum, 34(3s), 1648–1652. Retrieved from http://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/552
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