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Dr. Archana Rokade, Dr. Vasant Devkar, Dr. Shilpa C. Patil


Introduction: HELLP syndrome presents a diagnostic challenge due to its heterogeneous clinical presentation and potential for rapid deterioration. Understanding the underlying mechanisms contributing to HELLP syndrome is crucial for optimizing maternal and neonatal outcomes.
Methods: A retrospective case-control study was conducted, comparing pregnant women with HELLP syndrome (cases) to those without the syndrome (controls). Data were collected on demographic characteristics, clinical features, laboratory findings, maternal outcomes, neonatal outcomes, and long-term follow-up.
Results & Observation: Women with HELLP syndrome exhibited distinct demographic and clinical characteristics, including advanced maternal age, lower parity, and elevated blood pressure. Laboratory findings revealed thrombocytopenia and hepatic dysfunction in cases. Maternal outcomes indicated elevated rates of morbidity and mortality, while neonates born to mothers with HELLP syndrome experienced increased rates of prematurity and NICU admissions. Long-term follow-up data suggested potential implications for neurodevelopmental outcomes and chronic medical conditions among offspring.
Conclusion: HELLP syndrome represents a significant obstetric emergency with profound implications for maternal and neonatal health. Multidisciplinary care, early diagnosis, and aggressive management strategies are essential to optimize outcomes. Further research is needed to elucidate the pathophysiology of HELLP syndrome and develop targeted therapeutic approaches. Enhancing understanding and management of HELLP syndrome can improve care and support for affected individuals.

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How to Cite
Dr. Shilpa C. Patil, D. A. R. D. V. D. (2024). HELLP SYNDROME: PATHOPHYSIOLOGY, MANAGEMENT, AND NEONATAL OUTCOMES. Obstetrics and Gynaecology Forum, 34(3s), 576–585. Retrieved from http://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/319

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