CORRELATION BETWEEN PRE-OPERATIVE PLATELET COUNT AND SERUM CA-125 LEVEL IN EPITHELIAL OVARIAN CANCER: IMPLICATIONS FOR DIAGNOSTIC ACCURACY AND STAGING
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Abstract
The study investigates the correlation between pre-operative platelet count and serum CA-125 level in epithelial ovarian cancer patients, with a focus on its implications for diagnostic accuracy and staging. It explores how these two biomarkers, known for their prognostic value in ovarian cancer and their association with inflammation and immune evasion, relate to each other and their predictive potential for stage IV disease. Through a cohort of forty-two women diagnosed with epithelial ovarian cancer, the research reveals significant associations between platelet count and CA-125 levels, as well as their correlation with cancer histology and stage. The study underscores the utility of combining platelet count and CA-125 levels as a predictive model for accurately staging epithelial ovarian cancer and highlights the significance of CA-125 levels in identifying thrombocytosis in ovarian cancer patients. These findings offer insights into enhancing diagnostic accuracy and staging protocols for epithelial ovarian cancer.