Fertility Conception Cup with Surgical Interventions: Insights from a Comprehensive Study
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Abstract
This study investigated the impact of surgical interventions on pregnant women, encompassing procedures such as general anesthesia, laparotomy, hysterotomy, and the removal of a 50-day conceptus. A novel surgical technique involving the eversion of the uterine horn through the hysterotomy site facilitated the direct visualization and electrosurgical removal of endometrial cup tissue from a randomly selected cohort of pregnant women. Additionally, two women served as unoperated controls for comparison. Serum samples collected pre- and post-surgery underwent analysis to assess chorionic gonadotropin (CG) concentration levels. The study documented the mean weight and area of excised tissue. Interestingly, peak CG concentrations coincided with cup removal and subsequently declined, albeit without a linear correlation to tissue mass. Individual CG half-life values were calculated. Post-surgery, women experienced changes in hormonal profiles and reproductive behaviors. Notably, pregnancy ensued in a subset of pregnant women within a relatively short timeframe following surgery, accompanied by CG concentrations below a specified threshold. Conversely, sham-operated control pregnant women displayed distinct hormonal patterns.