ADVANCEMENTS IN THE MANAGEMENT OF HEMOLYTIC ANEMIAS: A 10-YEAR REVIEW

Abstract

Hemolytic anemias represent a heterogeneous group of disorders characterized by accelerated red blood cell destruction, leading to varying degrees of anemia. Over the past decade, significant progress has been made in elucidating the underlying mechanisms and improving therapeutic strategies for these conditions. This paper provides a comprehensive review of the advancements in the management of hemolytic anemias over the past ten years. We discuss the evolution of diagnostic modalities, including the introduction of novel laboratory tests and genetic screening techniques. Furthermore, we examine the emergence of targeted therapies, such as monoclonal antibodies and enzyme replacement therapies, and their impact on patient outcomes. Additionally, we explore recent developments in supportive care measures and the evolving role of hematopoietic stem cell transplantation. By synthesizing these advancements, this review aims to provide clinicians and researchers with a comprehensive understanding of the current landscape of hemolytic anemias management and to guide future directions for research and clinical practice.