BIOCHEMICAL AND IMMUNOLOGICAL RESPONSES TO USE DEXAMETHASONE IN RATS

Main Article Content

Salah M.M. Al Chalabi , Duha Zeki Al-Swefee
Abdul-Ameer Jawad Zayer , Asmaa I.Sail

Abstract

Abstract


This study was conducted to determine the side effects of dexamethasone n some physiological and immunological criteria, which included, Measuring sugar level, liver (ALT, AST, LDH, Total protein) and kidney function (urea, createnine), total and differential count of W.B.C,CRP, TNF-α ,IL6,IL10. thirty rats were divided into two groups (15\ rat). G1: This group was considered negative control injection with normal saline, G2: This group was injected with 2 mg\kg dexamethasone. The results showed a significant increase in the level of enzymesALT, AST and sugar levels and decreased level of total protein in the group treated with the drug, also showed, a significant decrease in the total number of W.B.C and a significant decreased in the level CRP, TNF-α, IL-6 and IL-10 in treated group as compared with control .


 

Article Details

How to Cite
Duha Zeki Al-Swefee , S. M. A. C. , & Asmaa I.Sail , A.-A. J. Z. ,. (2024). BIOCHEMICAL AND IMMUNOLOGICAL RESPONSES TO USE DEXAMETHASONE IN RATS. Obstetrics and Gynaecology Forum, 34(3s), 1498–1501. Retrieved from http://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/517
Section
Articles

Similar Articles

1 2 3 4 5 6 7 8 > >> 

You may also start an advanced similarity search for this article.