EVALUATING THE GENE EXPRESSION LEVEL OF IRF4 GENE IN TYPE 1 DIABETES
Main Article Content
Abstract
Abstract
Aims
In the present study, we aim to clarify the expression level of the IRF4 gene in TID patients compared with healthy controls.
Materials and Methods
We obtained PBMC samples from patients with T1D and healthy individuals aged 12–19 years, performed real-time PCR gene expression, and compared the results of T1D patients with those of healthy individuals.
Results
The PBMCs procured from T1D donors and healthy ones represent a unique opportunity to identify IRF4 gene expression levels. The data analysis identified the limited significance of the expression level between T1D patients and healthy controls.
Conclusion
Our findings point to the IRF4 gene as a potential target and therapeutic candidate against T1D, despite its limited role in supporting the immune-tolerance system.