A case of pemphigoid gestationis at a tertiary hospital in Gqeberha, South Africa

Abstract

Physiological skin changes during pregnancy include related skin structures such as glands, hair, nails and mucosa. Almost all pregnant women develop increased pigmentation of their skin to a certain degree. Localized pigmentation of certain areas of the body such as nipples, axillae, perineum, inner thigh and neck occurs more than other areas. These physiological changes may involve pruritus. Therefore, pruritus in pregnancy may be physiological or may be related to a flare of disorders present prior pregnancy. Pruritus may also be related to pregnancy specific dermatoses. These conditions among others include pemphigoid gestationis. This condition is associated with maternal morbidity and fetal risks. Early recognition and treatment of the condition often results in favourable outcomes for both the mother and the fetus.