ENDOGENOUS INTERFERON GAMMA LEVELS IN PREGNANT AND ABORTED WOMEN INFECTED WITH TOXOPLASMA GONDII AND CYTOMEGALOVIRUS IN WASIT-IRAQ
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Abstract
Abstract
The study was conducted in different areas of Wasit province, there is a 180 venous blood samples were collected from pregnant women infected with toxoplasmosis, cytomegalovirus, and mixed infection.
By using ELISA there is 21 cases 13.12% were positive for toxoplasmosis, 85 cases 53.12% were positive for cytomegalovirus, and 54 cases 33.75% were positive for mixed infection with the parasite and the virus. The highest concentration of interferon-gamma in women with acute toxoplasmosis (IgM) was 135.69 pg./ml, and on the other hand, it was lower in chronic infection (IgG) 38.8.8 pg./ml, compared to the control group, 49.12 pg./ml. The levels of interferon-gamma in pregnant women with acute toxoplasmosis is statistically highly significant compare within healthy women. The highest concentration of interferon-gamma in women infected with cytomegalovirus in acute infection was 238.93 pg./ml, while in chronic infection its level was 55.99 pg./ml. As for the level of interferon-gamma in pregnant women who had a co-infection with the parasite and the virus, it was 238.9 pg./ml for acute infection and 49.12 pg./ml for chronic infection.
The study was conducted in different areas of Wasit province, there is a 180 venous blood samples were collected from pregnant women infected with toxoplasmosis, cytomegalovirus, and mixed infection.
By using ELISA there is 21 cases 13.12% were positive for toxoplasmosis, 85 cases 53.12% were positive for cytomegalovirus, and 54 cases 33.75% were positive for mixed infection with the parasite and the virus. The highest concentration of interferon-gamma in women with acute toxoplasmosis (IgM) was 135.69 pg./ml, and on the other hand, it was lower in chronic infection (IgG) 38.8.8 pg./ml, compared to the control group, 49.12 pg./ml. The levels of interferon-gamma in pregnant women with acute toxoplasmosis is statistically highly significant compare within healthy women. The highest concentration of interferon-gamma in women infected with cytomegalovirus in acute infection was 238.93 pg./ml, while in chronic infection its level was 55.99 pg./ml. As for the level of interferon-gamma in pregnant women who had a co-infection with the parasite and the virus, it was 238.9 pg./ml for acute infection and 49.12 pg./ml for chronic infection.
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Altamemy A. A., R. A. A. A. ,. (2024). ENDOGENOUS INTERFERON GAMMA LEVELS IN PREGNANT AND ABORTED WOMEN INFECTED WITH TOXOPLASMA GONDII AND CYTOMEGALOVIRUS IN WASIT-IRAQ . Obstetrics and Gynaecology Forum, 34(3s), 1194–1196. Retrieved from http://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/444
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