DIFFERENTIAL EFFECT OF ANGIOTENSIN-CONVERTING ENZYME GENE I/D POLYMORPHISM ON TRAINING- AND DETRAINING-INDUCED CHANGES IN ADIPOSITY IN HEALTHY YOUNG KOREA MALES

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Jin-Hong Park, Hong-Seock Lee
Jong-Hyuck Kim, Sang-Mo Lee

Abstract

Background/Objectives: This prospective study examined the association between the ACE I/D polymorphism and the changes in adiposity induced by training and detraining. Most environmental factors were kept constant across participants.
Methods/Statistical analysis: A total of 99 healthy young Korean males who underwent an identical six months of exercise training and consecutive six months of detraining program(a longitudinal observation study). This measurement items were Body weight, body fat mass, % of body fat, waist-to-hip ratio, body mass index, blood pressure, genotyping the I/D polymorphism of ACE gene.
Findings: Pre-training adiposity was not differed by the ACE genotypes. But decrement of obesity with training was dependent on the genotype. Exercise-induced decrement of waist-to-hip ratio was greater in the ACE II genotype compared with ID and DD genotype. II genotype was more resistant to regaining of abdominal obesity related to detraining.
Improvements/Applications: In addition, note that the beneficial effects on adiposity of II genotype were mostly central but not general. This study demonstrated that change in body composition with training and detraining was strongly influenced by the ACE genotype.

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How to Cite
Hong-Seock Lee, J.-H. P., & Sang-Mo Lee, J.-H. K. (2024). DIFFERENTIAL EFFECT OF ANGIOTENSIN-CONVERTING ENZYME GENE I/D POLYMORPHISM ON TRAINING- AND DETRAINING-INDUCED CHANGES IN ADIPOSITY IN HEALTHY YOUNG KOREA MALES. Obstetrics and Gynaecology Forum, 34(3s), 73–77. Retrieved from http://obstetricsandgynaecologyforum.com/index.php/ogf/article/view/243
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